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Do not take two doses at one time. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

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An overdose of paroxetine can be fatal. What should I avoid while taking Paxil? Avoid driving or hazardous activity until you know how paroxetine will affect you. Your reactions could be impaired. Ask your doctor before taking a nonsteroidal anti-inflammatory drug such as aspirin, ibuprofen, naproxen, celecoxib, diclofenac, indomethacin, meloxicam, and others. Using an NSAID with Paxil may cause you to bruise or bleed easily. Drinking alcohol with this medicine can cause side effects. Paxil side effects Get emergency medical help if you have signs of an allergic reaction to Paxil or a severe skin reaction. Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive, more depressed, or have thoughts about suicide or hurting yourself. Call your doctor at once if you have: racing thoughts, decreased need for sleep, unusual risk-taking behavior, feelings of extreme happiness or sadness, being more talkative than usual; blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights; unusual bone pain or tenderness, swelling or bruising; changes in weight or appetite; easy bruising, unusual bleeding, coughing up blood; severe nervous system reaction – very stiff muscles, high fever, sweating, confusion, fast or uneven heartbeats, tremors, fainting; or low levels of sodium in the body – headache, confusion, slurred speech, severe weakness, loss of coordination, feeling unsteady. Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea. Common Paxil side effects may include: vision changes; weakness, drowsiness, dizziness, tiredness; sweating, anxiety, shaking; sleep problems ; loss of appetite, nausea, vomiting, diarrhea, constipation; dry mouth, yawning; infection; headache; or decreased sex drive, impotence, abnormal ejaculation, or difficulty having an orgasm. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. What other drugs will affect Paxil? Using Paxil with other drugs that make you drowsy can worsen this effect.

Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures. Tell your doctor about all your other medicines, especially: cimetidine, digoxin, St. Johns wort, tamoxifen, theophylline, tryptophan, warfarin ; a diuretic or water pill; heart rhythm medicine; HIV or AIDS medications; certain medicines to treat narcolepsy or ADHD – amphetamine, atomoxetine, dextroamphetamine, Adderall, Dexedrine, Evekeo, Vyvanse, and others; narcotic pain medicine – fentanyl, tramadol; medicine to treat anxiety, mood disorders, thought disorders, or mental illness – such as buspirone, lithium, other antidepressants, or antipsychotics; migraine headache medicine – sumatriptan, rizatriptan, zolmitriptan, and others; or seizure medicine – phenobarbital, phenytoin. This list is not complete. Other drugs may interact with paroxetine, including prescription and over-the-counter medicines, vitamins, and herbal products.
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Not all possible interactions are listed in this medication guide. Further information Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Paxil only for the indication prescribed. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. What is Paxil? Paxil is an antidepressant that belongs to group of drugs called selective serotonin reuptake inhibitors. Paroxetine affects chemicals in the brain that may be unbalanced in people with depression, anxiety, or other disorders. Paxil is used to treat depression, including major depressive disorder. Paxil is also used to treat panic disorder, obsessive-compulsive disorder, anxiety disorders, post-traumatic stress disorder, and premenstrual dysphoric disorder. Important Information You should not use Paxil if you are also taking pimozide or thioridazine. Do not use Paxil within 14 days before or 14 days after you have used an MAO inhibitor, such as isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, or tranylcypromine. Some young people have thoughts about suicide when first taking an antidepressant. Stay alert to changes in your mood or symptoms. Report any new or worsening symptoms to your doctor Seek medical attention right away if you have symptoms such as: agitation, hallucinations, muscle stiffness, twitching, loss of coordination, dizziness, warmth or tingly feeling, nausea, vomiting, diarrhea, fever, sweating, tremors, racing heartbeats, or a seizure. Before taking this medicine You should not use Paxil if you are allergic to paroxetine, or if you are also taking pimozide or thioridazine. Do not use an MAO inhibitor within 14 days before or 14 days after you take paroxetine. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.
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